Serotonin syndrome: Although rare, severe reactions are possible when codeine is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors medications used to treat depression.
Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, or changes in mental state including delirium and agitation. Coma and death are possible. If you are taking antidepressants, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks.
If you become pregnant while taking this medication, contact your doctor immediately. Infants born to mothers who have been taking codeine for long periods of time may experience dangerous withdrawal symptoms at birth.
Breast-feeding: Acetaminophen, codeine, and caffeine pass into breast milk. Some of the codeine dose is converted into morphine by the body, once it has been taken. For some people, this change happens much faster than for others. If this happens to a nursing mother, the baby is at risk of receiving a morphine overdose through the breast milk. If you are breast-feeding and are taking this medication, it may affect your baby.
Talk to your doctor about whether you should continue breast-feeding. Children: The safety and effectiveness of using this medication have not been established for children under 12 years old. Medications containing codeine should not be given to people under 18 years old for pain management after surgery to remove the tonsils and or adenoids.
Non-prescription products containing codeine should not be used by people under 18 years old. Recent evidence shows that young people who use opioids, including codeine, may be more likely to have problems with the misuse of medications and other substances later in life. Seniors: Seniors who take this medication may be more likely to experience side effects or worsening of preexisting medical conditions. If you are taking any of these medications, speak with your doctor or pharmacist.
Depending on your specific circumstances, your doctor may want you to:. An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter non-prescription , and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www. Tylenol NO. About this Medication.
How does this medication work? What will it do for me? This combination product contains three medications: acetaminophen, codeine, and caffeine.
Codeine belongs to the group of medications called narcotic analgesics. Caffeine belongs to the group of medications called stimulants. Acne Doctor Discussion Guide. Acne: Fact vs Myth Quiz. Acne Treatment Options Table. Eczema : Prescription Medication Options Table. Toenail Fungus: Treatment Options Table. Before using this medication, tell your doctor or pharmacist your medical history, especially of:.
This drug may make you dizzy or drowsy. Alcohol or marijuana cannabis can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana cannabis.
Before having surgery or certain medical procedures such as a heart stress test or a procedure to restore a normal heart rhythm if you have an unusually fast heartbeat , tell your doctor or dentist that you use this medication and about all the products you use including prescription drugs, nonprescription drugs, and herbal products. See also Warning section. It may harm an unborn baby. Discuss the risks and benefits with your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant, such as unusual sleepiness, difficulty feeding, trouble breathing, or unusual limpness.
Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Tell your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers such as morphine, hydrocodone , alcohol, marijuana cannabis , drugs for sleep or anxiety such as alprazolam, lorazepam, zolpidem , muscle relaxants such as carisoprodol, cyclobenzaprine , or antihistamines such as cetirizine, diphenhydramine.
Check the labels on all your medicines such as allergy or cough-and-cold products, pain relievers because they may also contain acetaminophen, caffeine, or ingredients that cause drowsiness.
Ask your pharmacist about using those products safely. Other medications can affect the removal of this product from your body, which may affect how this product works. Examples include azole antifungals such as ketoconazole , bupropion, fluoxetine, macrolide antibiotics such as erythromycin , HIV medications such as ritonavir , paroxetine, quinidine, rifamycins such as rifabutin, rifampin , certain drugs used to treat seizures such as carbamazepine, phenytoin , among others.
Avoid drinking large amounts of beverages containing caffeine coffee, tea, colas and eating large amounts of chocolate. Make sure laboratory personnel and all your doctors know you use this drug. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, give them naloxone if available, then call If the person is awake and has no symptoms, call a poison control center right away.
US residents can call their local poison control center at Canada residents can call a provincial poison control center. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case.
Ask your doctor or pharmacist if you should have naloxone available to treat opioid overdose. Teach your family or household members about the signs of an opioid overdose and how to treat it.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Selected from data included with permission and copyright by First DataBank, Inc. This copyrighted material has been downloaded from a licensed ata provider and is not for distribution, except as may be authorized by the applicable terms of use.
Conditions of use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals.
The information in not intend to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed in indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use and Privacy Policy.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of the oral solution or tablet, skip the missed dose and go back to your regular dosing schedule. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Acetaminophen and codeine combination oral solution or tablet can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong narcotic pain medicines.
Make sure you store the medicine in a safe and secure place to prevent others from getting it. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations.
You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website:www. There is a problem with information submitted for this request. Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health.
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